will wheels from a 1991 4wd chevy s10 blazer fit on a 2003 chevy 2wd s10

The 2wd/4wd does not matter it is the bolt pattern, 5bolt/6bolt etc. Yes.

the 2wd vs 4wd actually does matter. on the older ones anyways. the older body style werent interchangeable. if u tried putting a 91 4wd on to a 91 2wd it wouldnt fit cause the center of the 2wd is actually bigger then the 4wd which is backwards compared to most models. but the 4wd rims would fit on the 2wd

since the 2003 is basically the same frame & suspention l would have to say no.. but dont really know that for sure. might want to call a dealership or google around